• About
  • Partnerships
  • Challenges
  • Awards
  • Grant Opportunities
  • News

Engineered TALE Nucleases for Broad-Spectrum Resistance Against Cassava-Infecting Geminiviruses

Savithramma Dinesh-Kumar of the University of California, Davis, along with David Segal of the University of California, Davis and Vincent Fondong of Delaware State University in the U.S., seek to design custom TALE nucleases that target and cleave critical regions of DNA from cassava-infecting geminiviruses (CMGs) to completely inactivate the viruses. CMGs are a major threat to cassava production in Africa, and targeted nucleases could be used to engineer CMG resistance into staple African cassava varieties to promote regional food security.

More information about Protect Crop Plants from Biotic Stresses from Field to Market (Round 9)

Great ideas come from everywhere.

Sign up for email updates of the latest grant opportunities and awards.

View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.