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Drugs That Invert Selection for Resistance

Roy Kishony of Harvard University will seek to identify chemical entities that act as "selection inverters" which actively target antibiotic-resistant bacteria. Selection- inverters could be used in combination with traditional antibiotics to prevent resistance and possibly even drive a drug-resistant bacteria population back to drug sensitivity.

More information about Create Drugs and Delivery Systems to Limit Drug Resistance (Round 1)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.