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Development of a Pan-Anti-Anopheles Livestock Vaccine

Brian Foy of Colorado State University in the U.S. will use antibodies that bind essential proteins in the mosquito Anopheles in order to block malaria transmission. They have already produced antibodies that bind conserved mosquito antigens such as the glutamate-gated chloride channel and used them to supplement blood meals, which was lethal to feeding mosquitoes. They will test whether cattle injected with these antigens produce the corresponding antibodies that are also lethal to the mosquitoes that feed off them.

More information about New Approaches for Addressing Outdoor/Residual Malaria Transmission (Round 15)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.