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Development of a Non-Infectious Poliovirus Vaccine

James Flanegan of the University of Florida in the U.S. proposes to develop a non-infectious poliovirus vaccine using encapsidated replicons or mature empty capsids that retain full immunogenicity. Either approach can be potentially used to develop a new vaccine that can be safely used in a pre- or post-eradication world.

More information about The Poliovirus Endgame: Create ways to Accelerate, Sustain and Monitor Eradication (Round 6)

Great ideas come from everywhere.

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.