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Development of a Hand-held, DNA Aptamer-based Surface Enhanced Resonance Raman Scattering (SERS) Biosensor for Direct Identification and Quantitation of Biomarkers and Pathogens in Complex Biological Samples at Point-of-Care

Jonathan Blackburn of the University of Cape Town in South Africa will use tuberculosis as a model disease to develop a low-cost, hand-held biosensor that combines the selectivity of antigen-specific DNA aptamers with the exceptional specificity of Surface Enhanced Raman Spectroscopy in order to reliably quantify pathogen biomarkers present in patient specimens at the point-of-care.

More information about Grand Challenges Canada: Point-of-Care Diagnostics

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.