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Development of Extremophile Bacteriophage-based Vaccines

Samuel M. Duboise of the University of Southern Maine in the U.S., along with colleagues in Kenya, will develop a vaccine platform that uses bacteriophages that are structurally stable in one of Earth's most extreme environments - the hypersaline alkaline soda lakes of Kenya's Great Rift Valley. Vaccines produced using these engineered bacteriophages are expected to be inexpensive, stable, and easy to produce in regionally dispersed locations using common microbiological and biochemical methods that are highly scalable and adaptable for "just-in-time" production.

More information about Explore New Solutions for Global Health Priority Areas (Round 8)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.