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Blocking the P. falciparum Transporter PfCRT

Christine Hrycyna and Jean Chmielewski of Purdue University in the U.S. will develop novel dimeric drugs designed to block a key protein in the malaria parasite that limits the accumulation of anti-malarials in the parasite's digestive system. By inhibiting this protein, this new therapy could eliminate drug resistance in malaria parasites.

More information about Create New Ways to Protect Against Infectious Disease (Round 4)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.