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Biologic Contraceptive

Rachel Teitelbaum of Hervana, Ltd. in Israel will develop and test a biological vaginal formulation that produces a sperm-binding agent, which interferes with sperm motility or fertilization or both. It is hoped that this non-hormonal contraceptive will need only infrequent administration to maintain its effectiveness. In this project's Phase I research, Teitelbaum developed a lead formulation and demonstrated initial proof-of-principle that such an approach can provide effective contraception. In Phase II, Teitelbaum and her team will expand upon this proof-of-principle in animal models to arrive at a long-acting, safe, and effective contraceptive that is ready for evaluation in human trials.

More information about Create New Technologies for Contraception (Round 4)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.