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Bacterial Nano-Particles as Oral Vaccines Against Diarrhea

Garry Blakely of the University of Edinburgh in the United Kingdom will engineer a common gut bacterium to express antigens from pathogens that cause diarrhea onto nanoscale outer membrane vesicles. These nanoparticles could be the basis for a new generation of biocompatible oral vaccines that will protect against diarrheal disease.

More information about Apply Synthetic Biology to Global Health Challenges (Round 7)

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View the Grand Challenges partnership network

The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.