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Applying the Metagenomic Approach for the Detection of EsβL- and Carbapenemase-Producing Enteric Pathogens Recovered from Different Hosts

The project will study the genetic material from environmental samples from humans (healthy and ill), cattle and their meat to estimate the proportion of E. coli and K. pneumoniae in the microbiome. The main objective is to better understand the distribution of bacteria and its resistance genes, Escherichia coli and Klebsiella pneumoniae bacteria and extended spectrum beta-lactamase (EsβL) and carbapenemases encoding genes in distinct ecological sources.

More information about Grand Challenges Explorations - Brazil: New Approaches to Characterize the Global Burden of Antimicrobial Resistance

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit www.grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.