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Anti-Microbial/HIV-1 Peptide as a Vaginal Contraceptive

Nongnuj Tanphaichitr of the Ottawa Hospital Research Institute (formerly Ottawa Health Research Institute) in Canada will research whether the antimicrobial peptide LL-37 can be used simultaneously as a contraceptive and an anti-HIV treatment. LL-37 binds to specific sites on sperm which are thought not only to play key roles in egg fertilization but also interact with gp120 used by HIV to gain entry into cells.

More information about Create New Technologies for Contraception (Round 5)

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The Bill & Melinda Gates Foundation is part of the Grand Challenges partnership network. Visit grandchallenges.org to view the map of awarded grants across this network and grant opportunities from partners.