On June 3, 2014, Grand Challenges Explorations grants were announced for some 52 researchers from around the world. Each will receive $100,000 to conduct early-stage research projects focusing on one of five global health and development challenges selected for this Round.&nbsp; 
 
Moreover, three successful projects from previous Rounds were awarded grants for a second phase of funding and depending on the individual project, could receive funding of up to $1,000,000.00.&nbsp;

On June 3, 2014, Grand Challenges Explorations grants were announced for some 52 researchers from around the world. Each will receive $100,000 to conduct early-stage research projects focusing on one of five global health and development challenges selected for this Round.&nbsp;  Moreover, three successful projects from previous Rounds were awarded grants for a second phase of funding and depending on the individual project, could receive funding of up to $1,000,000.00.&nbsp;

Grand Challenges Explorations Round 12 Highlights

Inciting Healthy Behaviors: Nudge, Disrupt, Leapfrog, Reach (Round 12)

Kris Ansin of the Mali Health Organizing Project in the U.S. will work to improve the use of primary health clinics in Mali by identifying shortcomings in patients’ experiences at the clinics.

Improving the Patient Experience in Primary Care Clinics

Grand Challenges Explorations: Round 12 Highlights

Grand Challenges Explorations

Photo Galleries

Photo Gallery

Novel Enabling Tools and Models Supporting Development of Interventions for Enteric Dysfunction (Round 12)

Michel Bagnat of Duke University in the U.S. will study new genetic zebrafish models of acute secretory diarrhea and environmental enteric dysfunction, which are normally caused by infectious pathogens in humans, to study disease pathogenesis and facilitate development of new therapies.

Zebrafish Models of ASD and EED

Novel Enabling Tools and Models Supporting the Development of Interventions for Severe Diarrhea and Enteric Dysfunction: Zebrafish Models of ASD and EED

Innovations in Feedback and Accountability Systems for Agricultural Development (Round 12)

Eliane Ubalijoro and Myriam Gervais of McGill University in Canada will analyze methods to use the knowledge and expertise of rural women smallholder farmers in developing countries to better inform agricultural development projects.

Photovoice for Gender Responsive and Effective Innovation

Innovations in Feedback and Accountability Systems for Agricultural Development: Photovoice For Gender Responsive And Effective Innovation

Develop the Next Generation of Condom (Round 12)

Shengxi Chen of Arizona State University Foundation in the U.S. will produce a male condom using a material to mimic the surface of the skin for a more natural feel, coupled with a chemical to activate erection.

Condom Materials to Increase Pleasure and Enhance Erection

Develop the Next Generation of Condoms: Novel Materials To Increase Pleasure And Enhance Erection

Lijuan Yuan of Virginia Polytechnic Institute and State University in collaboration with others will develop a pig model with impaired intestinal function and altered types of gut microbes to mimic the condition of many children in developing countries who do not respond to vaccines against rotavirus infection, which causes infectious diarrhea.

Gnotobiotic Pig Model for Dysbiosis and Enteric Immunity

Novel Enabling Tools and Models Supporting the Development of Interventions for Severe Diarrhea and Enteric Dysfunction: Gnotobiotic Pig Model For Dysbiosis And Enteric Immunity

Ranjan Shrestha of SNV (Netherlands Development Organization) in Rwanda will facilitate communication between smallholder coffee producers and district coffee taskforces to boost the coffee sector in Rwanda.

Smart Accountability in the Rwandan Coffee Sector

Innovations in Feedback and Accountability Systems for Agricultural Development: Smart Accountability In The Rwandan Coffee Sector

The One Health Concept: Bringing Together Human and Animal Health for New Solutions (Round 12)

Charles Long of the College of Veterinary Medicine and Biomedical Sciences in the U.S. will develop a strategy for generating single vaccines against diseases that infect both humans and animals (zoonotic) for use in both species that can be locally produced in goat milk.

Single Dose, Multivalent Vaccine for Zoonotic Diseases

The One Health Concept: Single Dose, Multivalent Vaccine For Zoonotic Diseases

Marya Lieberman of the University of Notre Dame in the U.S. will produce an inexpensive paper card that can easily and quickly measure the quality of over 50 common drugs used to treat both humans and animals.

Printed Test Cards for Rapid Field Screening of Medications

The One Health Concept: Printed Test Cards For Rapid Field Screening of Medications

Tanvir Huda of ICDDRB in Bangladesh will improve care and nutrition for pregnant women and young children by setting up a system whereby mobile phones are used to receive nutritional information and financial incentives for positive health-related behavior, such as attending clinics.

Integrating Cash Transfer and Nutrition Promotion with Mobile

Inciting Healthy Behaviors: nudge, leapfrog, disrupt, reach: Integrating Cash Transfer & Nutrition Promotion With Mobile

Robert Gorkin of the University of Wollongong in Australia will synthesize and test tough hydrogels as an alternative material to latex for making male condoms with enhanced tactile (touch) sensitivity, thereby improving sexual experience.

Durable and Sensitive Tough Hydrogel Condoms

Develop the Next Generation of Condoms: Durable And Sensitive Tough Hydrogel Condoms

Prakarsh Singh of Amherst College in the U.S. will test different financial incentives to motivate staff at day care centers in India to improve their performance.

Nudging Caregivers and Mothers towards Healthy Behavior

Inciting Healthy Behaviors: nudge, leapfrog, disrupt, reach: Nudging Caregivers And Mothers Towards Healthy Behavior

Kris Ansin of the Mali Health Organizing Project in the U.S. will work to improve the use of primary health clinics in Mali by identifying shortcomings in patients’ experiences at the clinics and working with staff to address them.