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Grand Challenges is a family of initiatives fostering innovation to solve key global health and development problems. Each initiative is an experiment in the use of challenges to focus innovation on making an impact. Individual challenges address some of the same problems, but from differing perspectives.

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Top Priorities for Maternal, Neonatal, and Child Health in Africa

Grand Challenges Africa
27 Nov 2019

2019 Grand Challenges Annual Meeting Call-to-Action

Grand Challenges
30 Oct 2019

Voices for Economic Opportunity

Grand Challenges
18 Sep 2019
GCE_Round24

Innovations for Improving the Impact of Health Campaigns (Round 24)

Grand Challenges Explorations
18 Sep 2019

Data Science Approaches to Improve Maternal and Child Health in Africa

Grand Challenges Africa
13 Mar 2019

Emerging Technologies for New Solutions in Global Health Priority Areas (Round 23)

Grand Challenges Explorations
19 Feb 2019

Increasing Demand for Vaccination Services (Round 23)

Grand Challenges Explorations
19 Feb 2019

Environmental niches of Salmonella Typhi (Round 23)

Grand Challenges Explorations
19 Feb 2019

Neglected Tropical Diseases Data Innovation Incubator

Grand Challenges
28 Jan 2019
Healthy Birth

Achieving Healthy Growth

Grand Challenges in Global Health
1 Nov 2011
Healthy Birth

Preventing Preterm Birth

Grand Challenges in Global Health
1 Nov 2011
Discover Biomarkers of Health and Disease

Discover Biomarkers of Gut Function

Grand Challenges in Global Health
1 Nov 2011

Grand Challenges Explorations - India

Grand Challenges India
1 Oct 2011

Explore New Solutions for Global Health Priority Areas (Round 8)

Grand Challenges Explorations
23 Aug 2011

Apply Synthetic Biology to Global Health Challenges (Round 8)

Grand Challenges Explorations
23 Aug 2011

Explore Nutrition for Healthy Growth of Infants and Children (Round 8)

Grand Challenges Explorations
23 Aug 2011

Design New Approaches to Optimize Immunization Systems (Round 8)

Grand Challenges Explorations
23 Aug 2011

Protect Crop Plants from Biotic Stresses From Field to Market (Round 8)

Grand Challenges Explorations
23 Aug 2011

China Tsinghua University - Grand Challenges Explorations

Grand Challenges Explorations
1 Apr 2011

The Poliovirus Endgame: Create Innovative Ways to Accelerate, Sustain, and Monitor Eradication (Round 7)

Grand Challenges Explorations
15 Mar 2011

Apply Synthetic Biology to Global Health Challenges (Round 7)

Grand Challenges Explorations
15 Mar 2011

Create the Next Generation of Sanitation Technologies (Round 7)

Grand Challenges Explorations
15 Mar 2011

Design New Approaches to Cure HIV Infection (Round 7)

Grand Challenges Explorations
15 Mar 2011

Explore Nutrition for Healthy Growth of Infants and Children (Round 7)

Grand Challenges Explorations
15 Mar 2011

Create Low-Cost Cell Phone-Based Solutions for Improved Uptake and Coverage of Childhood Vaccination (Round 7)

Grand Challenges Explorations
15 Mar 2011

Saving Lives at Birth (Round 1)

Grand Challenges for Development
9 Mar 2011
Discover Biomarkers of Health and Disease

Discover Biomarkers of Tuberculosis

Grand Challenges in Global Health
1 Feb 2011

The Poliovirus Endgame: Create ways to Accelerate, Sustain and Monitor Eradication (Round 6)

Grand Challenges Explorations
19 Aug 2010

Create Low-Cost Cell Phone-Based Applications for Priority Global Health Conditions (Round 6)

Grand Challenges Explorations
19 Aug 2010

Create New Technologies to Improve the Health of Mothers and Newborns (Round 6)

Grand Challenges Explorations
19 Aug 2010

Create the Next Generation of Sanitation Technologies (Round 6)

Grand Challenges Explorations
19 Aug 2010

Design New Approaches to Cure HIV Infection (Round 6)

Grand Challenges Explorations
19 Aug 2010

Create New Technologies for Contraception (Round 5)

Grand Challenges Explorations
25 Mar 2010

Create New Technologies to Improve the Health of Mothers and Newborns (Round 5)

Grand Challenges Explorations
25 Mar 2010

Create New Ways to Protect Against Infectious Disease (Round 5)

Grand Challenges Explorations
25 Mar 2010

Create Low-Cost Cell Phone-Based Applications for Priority Global Health Conditions (Round 5)

Grand Challenges Explorations
25 Mar 2010

Create New Ways to Prevent or Cure HIV Infection (Round 2)

Grand Challenges Explorations
3 Sep 2008

Create New Vaccines for Diarrhea, HIV, Malaria, Pneumonia, and Tuberculosis (Round 2)

Grand Challenges Explorations
3 Sep 2008

Create New Ways of Protecting Against Infectious Diseases (Round 2)

Grand Challenges Explorations
3 Sep 2008

Create New Tools to Accelerate the Eradication of Malaria (Round 2)

Grand Challenges Explorations
3 Sep 2008

Create Drugs and Delivery Systems to Limit Drug Resistance (Round 2)

Grand Challenges Explorations
3 Sep 2008

Explore the Basis of Latency in Tuberculosis (Round 2)

Grand Challenges Explorations
3 Sep 2008

Create New Ways of Protecting Against Infectious Diseases (Round 1)

Grand Challenges Explorations
31 Mar 2008

Create Drugs and Delivery Systems to Limit Drug Resistance (Round 1)

Grand Challenges Explorations
31 Mar 2008

Explore the Basis of Latency in Tuberculosis (Round 1)

Grand Challenges Explorations
31 Mar 2008

Create New Ways to Prevent or Cure HIV Infection (Round 1)

Grand Challenges Explorations
31 Mar 2008
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