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Challenges

Grand Challenges is a family of initiatives fostering innovation to solve key global health and development problems. Each initiative is an experiment in the use of challenges to focus innovation on making an impact. Individual challenges address some of the same problems, but from differing perspectives.

Biological Vector Control

Develop a Biological Strategy to Deplete or Incapacitate a Disease-transmitting Insect Population

Grand Challenges in Global Health

1 Dec 2003

Crop Biofortification

Create a Full Range of Optimal, Bioavailable Nutrients in a Single Staple Plant Species

Grand Challenges in Global Health

1 Dec 2003

Create Effective Single Dose Vaccines That Can Be Used Soon After Birth

Create Effective Single Dose Vaccines That Can Be Used Soon After Birth

Grand Challenges in Global Health

1 Dec 2003

Protective Immunity

Learn Which Immunological Responses Provide Protective Immunity

Grand Challenges in Global Health

1 Dec 2003

Drug Resistance

Discover Drugs and Delivery Systems that Minimize the Likelihood of Drug Resistant Micro-organisms

Grand Challenges in Global Health

1 Dec 2003

Devise Reliable Tests in Model Systems to Evaluate Live Attenuated Vaccines

Grand Challenges in Global Health

1 Dec 2003

Curing Chronic Infection

Create Immunological Methods that can Cure Chronic Infections

Grand Challenges in Global Health

1 Dec 2003

Develop Needle-Free Delivery Systems

Develop Needle-Free Delivery Systems

Grand Challenges in Global Health

1 Dec 2003

Antigen Design

Solve How to Design Antigens for Effective, Protective Immunity

Grand Challenges in Global Health

1 Dec 2003

Create Therapies that Can Cure Latent Infection

Create Therapies that Can Cure Latent Infection

Grand Challenges in Global Health

1 Dec 2003

Prepare Vaccines that Do Not Require Refrigeration

Prepare Vaccines that Do Not Require Refrigeration

Grand Challenges in Global Health

1 Dec 2003

Chemical Vector Control

Develop a Chemical Strategy to Deplete or Incapacitate a Disease-transmitting Insect Population

Grand Challenges in Global Health

1 Dec 2003

Develop Technologies that Permit Quantitative Assessment of Population Health Status

Develop Technologies that Permit Quantitative Assessment of Population Health Status

Grand Challenges in Global Health

1 Dec 2003

Point-of-Care Diagnostics

Develop Technologies that Allow Assessment of Multiple Conditions and Pathogens at Point-of-Care

Grand Challenges in Global Health

1 Dec 2003

Create New Ways of Protecting Against Infectious Diseases (Round 1)

Grand Challenges Explorations

31 Mar 2008

Create Drugs and Delivery Systems to Limit Drug Resistance (Round 1)

Grand Challenges Explorations

31 Mar 2008

Explore the Basis of Latency in Tuberculosis (Round 1)

Grand Challenges Explorations

31 Mar 2008

Create New Ways to Prevent or Cure HIV Infection (Round 1)

Grand Challenges Explorations

31 Mar 2008

Create New Ways to Prevent or Cure HIV Infection (Round 2)

Grand Challenges Explorations

3 Sep 2008

Create New Vaccines for Diarrhea, HIV, Malaria, Pneumonia, and Tuberculosis (Round 2)

Grand Challenges Explorations

3 Sep 2008

Create New Ways of Protecting Against Infectious Diseases (Round 2)

Grand Challenges Explorations

3 Sep 2008

Create New Tools to Accelerate the Eradication of Malaria (Round 2)

Grand Challenges Explorations

3 Sep 2008

Create Drugs and Delivery Systems to Limit Drug Resistance (Round 2)

Grand Challenges Explorations

3 Sep 2008

Explore the Basis of Latency in Tuberculosis (Round 2)

Grand Challenges Explorations

3 Sep 2008

Create New Technologies for Contraception (Round 5)

Grand Challenges Explorations

25 Mar 2010