Dr. Ify Aniebo
Associate Professor of Molecular Biology and Genomics
African Centre of Excellence for Genomics of Infectious Disease (ACEGID)
About Ify
Growing up in Nigeria, Ify Aniebo and her childhood best friend both loved comic books. When they were 7 years old, both girls got sick with malaria and were admitted to the hospital. Both received injections of chloroquine, the first-line antimalarial drug at the time. Only Ify survived, and she couldn't understand why.
Using her favorite comic, the X-Men, as an analogy, her father's friend explained that it was likely her friend was infected with a new strain of the malaria parasite that had mutated to evade treatment. By the early 2000s, drug-resistant strains had become so pervasive that they rendered chloroquine ineffective.
"For me, understanding how parasites could become like little X-Men was amazing. This wasn't something that just happens in a comic. It really happens," said Ify, who became a molecular geneticist because she was obsessed with understanding DNA, how it affects the malaria parasite's mutating superpower, and how scientists can stop it.
She is now integrating genomics data into Nigeria's malaria surveillance system, which currently captures just 16% of the country's malaria cases and is run during the National Malaria Indicator Survey (MIS) which is run only every four years. Her goal is to make genomics data an essential part of Nigeria's malaria elimination strategy, turn surveillance into an annual exercise, and expand its utility to other diseases.
She collected 10,000 blood samples from children in all 36 states in Nigeria. These samples will undergo genetic sequencing, to make it possible to identify, track, and control the malaria parasites that are becoming drug resistant. Finally, the data will be shared in an easy-to-understand dashboard to enable evidence-based decision making for public health officials.
"I'm trying to change the way we think about using genomic data to make decisions, not just in malaria but to also have long-lasting impact on other infectious diseases as well," said Ify.
Ify moved to the U.K. when she was 11 years old. After 25 years, she returned to Nigeria despite its challenging research environment. Power outages interrupt sequencing runs, procuring lab supplies is costly and slow, gridlocked traffic steals hours of productivity, and runaway inflation squeezes her budget. But she is where she wants to be.
"I'm British and also Nigerian. It was very difficult to ignore the problems there when I clearly had ideas about what the solutions could be," she said. "It simply wasn't something that I could ignore."
Key Publications
Investment in African research and development will boost health and economic growth.
Population assessment of health system performance in 16 countries.
Pf7: an open dataset of plasmodium falciparum genome variation in 20 000 worldwide samples.
Rethinking malaria: Governance lessons from other disease programs.
Colonialism, malaria, and the decolonization of global health.
Open letter to international funders of science and development in Africa.
Open letter to international funders of science and development in Africa.
Genomic surveillance could make a big difference in the fight against malaria.
Accurate whole human genome sequencing using reversible terminator chemistry.
Grand Challenges Awards
Strengthening Nigeria's Surveillance System for Malaria Elimination by Integrating Molecular and Genomic Data
Initiative: Grand Challenges Global Call-to-Action
Challenge: Calestous Juma Science Leadership Fellowship
Learn More About This Award
October 6, 2021
Major Funding Awards and Honors
Harvard Takemi Fellow in International Health (2019-2021)
Senior Fellow, Aspen Institute (2016)
Recognition by the Mayor of London for science innovation (2016)
Fully funded Scholarship by Exxon Mobil (2011)
Fully funded Scholarship by the Wellcome Trust & Tropical Network Fund
Fellow, Nigeria Leadership Initiative (2011)
Winner Young Person of the Year (2010)
Winner Best use of Science (2010)
In the News
Harnessing the Power of Science Against Malaria
A New Model for Global Health and Development Innovation
Strengthening pharmaceutical manufacturing in Nigeria