The TB Vaccine Accelerator, a program to strengthen the pipeline of tuberculosis (TB) vaccine candidates and enable a more rational and accelerated vaccine development process, is launching a grant opportunity that is part of the Grand Challenges in Global Health—a large set of grant programs aimed at overcoming persistent bottlenecks that prevent the creation of effective health solutions for the developing world.
This grant opportunity, the first public request for applications (RFA) launched by the TB Vaccine Accelerator, focuses on two interrelated program goals:
- To develop novel approaches to vaccination against Mycobacterium tuberculosis (Mtb), with a particular focus on approaches that aim to induce protection against infection with Mtb; and
- To develop models of natural Mtb transmission and methods for defining the relevant molecular and biological characteristics of naturally transmitted mycobacteria and their interactions with vertebrate hosts.
This opportunity closed on November 26, 2012.